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UNUSUAL LYMPHATIC DRAINAGE TO CONTRALATERAL ROTTER'S LYMPH NODES IN BREAST CANCER: A SPECT/TC LYMPHOSCINTIGRAPHY CASE STUDY

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Received: October 14 2025
Published: October 15 2025
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Lymphatic drainage of the breast occurs mainly in ipsilateral axillary nodes, but up to 20–30% of
cases may present drainage to other locations, although it is usually coupled to ipsilateral axillary
nodes. Contralateral axillary drainage in daily clinical practice is very rare (0-2%), even more
without associated ipsilateral drainage. We present the case of a 71-year-old woman with a personal
history of ductal/lobular carcinoma at 49 years on the left breast and a second primary invasive
lobular carcinoma in the right breast. Preoperative lymphoscintigraphy showed absence of
lymphatic drainage in the ipsilateral axilla but unusual lymphatic drainage was detected in the
contralateral Rotter's lymph nodes as confirmed by SPECT/TC imaging

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UNUSUAL LYMPHATIC DRAINAGE TO CONTRALATERAL ROTTER’S LYMPH NODES IN BREAST CANCER: A SPECT/TC LYMPHOSCINTIGRAPHY CASE STUDY. (2025). EuroMediterranean Biomedical Journal, 16. https://doi.org/10.3269/1970-5492.2021.16.22