GAP JUNCTIONS, HEMICHANNELS AND CONNEXINS AND THEIR ROLE IN THE NEUROVASCULAR UNIT
Abstract
Recent advances have come to suggest that connexins (Cxs), the core gap junction (GJs) and
hemichannels (HCs) composing proteins, play a crucial role in neurodegenerative and
neuroprotective conditions. GJs and HCs syncytia in the complex neuroglial network allows glial
cells to support and even modulate neuronal function in both physiological and pathological
conditions. In this review we aim at reviewing the current knowledge in the context of neuroglial
crosstalk and neurovascular units (NVU) and at delivering up-to-date insights on cell populations
interplay in physiological and pathological central nervous system (CNS) conditions.
Metrics
Citations and online attention from Dimensions, Altmetric and PlumX.
License
Copyright (c) 2025 The Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.