CLINICAL ROLE OF CRITICAL CARE ECHOCARDIOGRAPHY IN SEPTIC PATIENTS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS
Abstract
Critical care echocardiography (CCE) use is rapidly growing and echocardiography is
recommended as first-line approach to patients presenting with shock. In most cases the prompt use
of CCE offers the opportunity to quickly identify the shock aetiology, with the advantage of being a
non-invasive point-of-care tool. Septic shock is among the most common diagnoses of hypotension
both in the emergency department and in the intensive care unit. CCE may have a substantial role in
sepsis. Initially it may exclude other causes of hypotension and support the appropriateness of
fluid-resuscitation. After the initial resuscitation, CCE may help in directing fluid management,
guiding the “optimization” and “stabilization” phases, identifying among others conditions of fluid
responsiveness. In a later stage, CCE can be likewise helpful for the “de-escalation” phase of fluid
management, supporting a goal-directed fluid removal. We summarize the current knowledge on
the use of CCE in sepsis from the gap in knowledge with opened questions for future research to
the use of CCE from clinical perspectives in guiding fluid and pharmacological therapy
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