Original Articles
Vol. 14 (2019)
https://doi.org/10.3269/1970-5492.2019.14.17
RAPIDLY PROGRESSING SYSTEMIC LUPUS ERYTHEMATOSUS IN A YOUNG PATIENT
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: October 20 2025
Published: January 12 2026
Published: January 12 2026
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Systemic lupus erythematosus (SLE) has a variable clinical expression and can be manifested by a single
organ or a multiorgan dysfunction. Patients with this condition have higher associated mortality rates, even
when the disease seems clinically stable for many years. An event can occur that deregulates the disease at
any given time, making it active or uncontrolled again. In uncontrolled patients, the diagnosis is sometimes
difficult and both the approach and treatment are crucial for a favorable outcome. This case report describes
the challenging management of a young patient who presented neuropsychiatric manifestations,
hematological abnormalities and a rapid development of multiorgan dysfunction. During the patient’s
hospitalization, three cerebrovascular accidents were registered with a continued worsening of the clinical
status, resulting in her death after 33 days. Even with immunosuppression therapy there were several
complications, some of which were promptly resolved; however, it was not possible to stop a rapidly
progressing autoimmune induced multiorgan failure. The unique features presented by this patient and the
rapid progression of the disease are an important alert for all physicians that work in the emergency room
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How to Cite
RAPIDLY PROGRESSING SYSTEMIC LUPUS ERYTHEMATOSUS IN A YOUNG PATIENT. (2026). EuroMediterranean Biomedical Journal, 14. https://doi.org/10.3269/1970-5492.2019.14.17
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