Original Articles
Vol. 14 (2019)
https://doi.org/10.3269/1970-5492.2019.14.31
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: October 20 2025
Published: January 12 2026
Published: January 12 2026
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Head circumference is the auxological parameter that most correlates with developmental anomalies in
childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines
microcephaly and macrocephaly, respectively. The aim of this retrospective study was to explore
anthropometric parameters and clinical characteristics among subjects with abnormalities in HC who had
been referred for developmental assessment. One hundred and sixty four subjects with microcephaly and 144
subjects with macrocephaly were enrolled from birth to 18 months of age. Head circumference at birth and
the association with variables related to maternal health status, gestational age, growth pattern, brain imaging
and clinical characteristics were analyzed. In some cases, an etiological diagnosis was made. In the two
considered conditions, we found different anthropometric and clinical associations, some of which were
statistically significant, with implications for ongoing neurodevelopmental surveillance.
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How to Cite
MICROCEPHALY AND MACROCEPHALY. A STUDY ON ANTHROPOMETRIC AND CLINICAL DATA FROM 308 SUBJECTS. (2026). EuroMediterranean Biomedical Journal, 14. https://doi.org/10.3269/1970-5492.2019.14.31
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