Original Articles
Vol. 14 (2019)
https://doi.org/10.3269/1970-5492.2019.14.40

TREATMENT OF PARADOXICAL VOCAL FOLD MOTION IN A 12-YEAR-OLD PATIENT WITH PATAU’S SYNDROME

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Received: October 20 2025
Published: January 12 2026
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Authors

Francesco Freni
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
Bruno Galletti
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
Viviana Nicastro
vivianica@hotmail.it
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
Pietro Abita
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
Annamaria Zagaria
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
Rocco Bruno
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
Francesco Galletti
Department of Adult and Development Age Human Pathology “Gaetano Barresi”, Unit of Otorhinolaryngology, University of Messina, Italy, Italy.
We describe the case of a 12-year-old girl with paradoxical vocal fold motion (PVFM) secondary to
partial Patau’s syndrome, successfully treated with botulinum toxin A (BTX-A) injection to the vocal
folds. We performed follow-up 1 and 3 months after the injection, with no relapse. Paradoxical vocal
fold motion (PVFM) is a poorly understood disorder of episodic dyspnea. The aim of this case is to
highlight the use of a mini-invasive surgical technique to treat PVFM in a patient otherwise forced to
undergo a permanent tracheostomy, reducing the peri- and postoperative risks of its management

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TREATMENT OF PARADOXICAL VOCAL FOLD MOTION IN A 12-YEAR-OLD PATIENT WITH PATAU’S SYNDROME. (2026). EuroMediterranean Biomedical Journal, 14. https://doi.org/10.3269/1970-5492.2019.14.40
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