Original Articles

THE ROLE OF METACOGNITION IN MULTIPLE SCLEROSIS: A CLINICAL STUDY AND ASSESSMENT OF POSSIBLE CORRELATION WITH ANXIETY, DEPRESSION AND COPING STRATEGIES

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Published: January 12 2026
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The current study aimed to explore the relationships between metacognition and anxiety, depression, and coping strategies in MS patients, compared to healthy subjects. The study was conducted on a group of 50 MS patients and a control group of 50 healthy volunteers matched for gender, age, level of education and social status. Metacognitions were assessed with the Metacognitions Questionnaire-30, while anxiety and depression were assessed with the Hospital Anxiety and Depression Scale, and coping strategies were assessed with the Brief COPE. Results did not show significant differences between metacognitive factors for MS patients and healthy subjects. However, we found specific, contrasting correlations between the MS group and the control group. The results of this study could have some implications for clinical practice. Given the relationship between metacognitions and negative emotions, “psychological intervention”, based on the metacognitive approach, could have positive effects on MS patients.

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THE ROLE OF METACOGNITION IN MULTIPLE SCLEROSIS: A CLINICAL STUDY AND ASSESSMENT OF POSSIBLE CORRELATION WITH ANXIETY, DEPRESSION AND COPING STRATEGIES. (2026). EuroMediterranean Biomedical Journal, 13. https://doi.org/10.3269/1970-5492.2018.13.9