Original Articles
Vol. 13 (2018)
https://doi.org/10.3269/1970-5492.2018.13.26

MITOCHONDRIA IN MAMMALIAN OOCYTES AND EARLY EMBRYOS. A REVIEW ON MORPHOLOGICAL AND FUNCTIONAL STUDIES

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Received: October 22 2025
Published: January 12 2026
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Authors

Manuel Belli
Dept. of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy, Italy.
Sevastiani Antonouli
Dept. of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy, Italy.
Stefania Annarita Nottola
stefania.nottola@uniroma1.it
Dept. of Anatomy, Histology, Forensic Medicine and Orthopaedics, La Sapienza University of Rome, Rome, Italy, Italy.
Mitochondria are the most abundant organelles in mammalian oocytes and early embryos. The central role of mitochondria in the establishment of developmental competence of oocytes and early embryos come out from basic research in experimental models and clinical studies, including those from Assisted Reproductive Technologies (ARTs) such as in vitro fertilization and embryo culture. We here review major concerns about mitochondrial bioenergetic function and morphology as well as their involvement in oocyte and early embryo development.

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MITOCHONDRIA IN MAMMALIAN OOCYTES AND EARLY EMBRYOS. A REVIEW ON MORPHOLOGICAL AND FUNCTIONAL STUDIES. (2026). EuroMediterranean Biomedical Journal, 13. https://doi.org/10.3269/1970-5492.2018.13.26
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