Original Articles

IDIOPATHIC NEONATAL AORTIC ARCH THROMBOSIS: A CASE REPORT

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Published: January 12 2026
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Background: Neonatal aortic arch thrombosis is a rare but life threatening condition. correct diagnosis and an appropriate therapeutic approach are fundamental to prevent death or severe injuries.
Case presentation: we report a case of spontaneous aortic arch thrombosis in a term newborn, who presented with suggestive signs of aortic coarctation immediately after birth. Despite the initiation of anticoagulant therapy, a massive increase in size of thrombus with evidence of coronary involvement was noted. Thrombolytic treatment was performed with thrombus resolution. Death occurred after a few days due to widespread brain haemorrhage.
Conclusion: To date, no definitive guidelines have been published for the treatment of neonatal aortic arch thrombosis, and only anecdotal reports are available. A multidisciplinary approach is fundamental in order to evaluate the risk:benefit ratio of proposed medical and surgical interventions. Further studies are needed to improve consensus evidence based guidelines and ensure appropriate approaches to this condition.

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IDIOPATHIC NEONATAL AORTIC ARCH THROMBOSIS: A CASE REPORT. (2026). EuroMediterranean Biomedical Journal, 9. https://doi.org/10.3269/1970-5492.2014.9.5