Original Articles

OCULAR MANIFESTATIONS OF MULTIPLE SCLEROSIS: EVALUATION OF THE RETINAL NERVE FIBER LAYER ATROPHY

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Published: January 12 2026
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Multiple sclerosis (MS) is the most common and complex neurological disease in young adults, characterised by demyelination and axonal loss. Many neuro-ophthalmological manifestations can occur during the course of the illness, and Optic neuritis (ON) is both the most frequent and the best known. The research herein presented has highlighted, through the execution of instrumental exams, that people with MS and with episodes of ON, show a reduction in the medium depth of the nerve retinal fibres (a datum which is already present in literature). It has also been shown that people with MS without previ- ous episodes of ON present a sectorial reduction in the depth of the retinal nerve fibers. The discovery of this alteration could shed light on the pathology prognosis and also enhance the patient’s quality of life.

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OCULAR MANIFESTATIONS OF MULTIPLE SCLEROSIS: EVALUATION OF THE RETINAL NERVE FIBER LAYER ATROPHY. (2026). EuroMediterranean Biomedical Journal, 6. https://doi.org/10.3269/1970-5492.2011.6.4