Original Articles

EVALUATION OF EFFECTIVENESS OF VIPER SERUM FOR TOPICAL USE AS FACIAL ANTI-AGING

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Published: April 7 2026
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In Aesthetic Medicine a revolution to prevent skin aging and fight facial wrinkles has been the introduction into the market (for aesthetic purposes) of botulinum toxin. The action of the toxin is to weaken the muscle through a partial paralysis of peripheral nerves, with a relaxation of the skin. In our study, we tried to assess the anti-aging efficacy of three different oligopeptide preparates to prevent skin aging of the upper third of the face. Within our O.U. Plastic Surgery, we selected, at random, 12 volunteer subjects. We used three preparations will mimic the action of botulinum toxin, through transcutaneous absorption. The two main components are ARGIRELINE® and SYN®-AKE. Short-term treatment showed a general tendency to a reduction in contractile status at the level of the corrugator and orbicularis muscles. The long-term treatment, instead, showed a valid effect at the level of the frontalis muscle.

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EVALUATION OF EFFECTIVENESS OF VIPER SERUM FOR TOPICAL USE AS FACIAL ANTI-AGING. (2026). EuroMediterranean Biomedical Journal, 4. https://doi.org/10.4081/embj.2009.531