EVALUATION OF THE EFFICACY OF CALENDULA OFFICINALIS TINCTURE IN SURGICAL WOUND CARE TREATMENT: A FACTORIAL MONOCENTRIC RANDOMIZED PHASE III SINGLE-BLIND CLINICAL STUDY
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The aim of this study was to compare wound care treatment with Iodine solution against tincture made of a natural plant, Calendula officinalis. This plant is famous for the anti-flogistic and antibacterial action.
We have selected 28 patients, randomized in two arms of treatment: arm-A (medication with Betadine®); arm B (medication with Calendula officinalis).
We have measured wound areas at the 3rd and 15th day of medications by a digital photo system and the software Adobe Photoshop.
To evaluate the flogistic parameters, we have used the same software, considering different colour parameters.
Statistic analyses have shown a significant decrease of both areas and flogistic parameters in both arms of treatment In conclusion, the Calendula officinalis has shown re-epithelizing anti-flogistic effects, without damage or obstacle of the healing process.
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