Original Articles
Vol. 16 (2021)

WHAT’S IN CURCUMIN’S MIND? THE POTENTIAL ROLE OF CURCUMINOIDS IN THE TREATMENT OF ALZHEIMER’S DISEASE

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Published: October 15 2025
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Paola Marzullo
paola.marzullo@unipa.it
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies -STEBICEF, University of Palermo, Italy.
Silvestre Buscemi
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies -STEBICEF, University of Palermo, Italy.
Neurodegenerative diseases (NDs) are one of major public health problems and their impact is continuously growing. Curcumin has been proposed for the treatment of several of these pathologies, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) due to the ability of this molecule to reduce inflammation and aggregation of involved proteins. Nevertheless, the poor metabolic stability and bioavailability of curcumin reduce the possibilities of its practical use. In this review will be highlighted recent results on curcumin and curcuminoids in the search of new effective therapeutics agents against NDs, with particular emphasis on AD.

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WHAT’S IN CURCUMIN’S MIND? THE POTENTIAL ROLE OF CURCUMINOIDS IN THE TREATMENT OF ALZHEIMER’S DISEASE. (2025). EuroMediterranean Biomedical Journal, 16. https://doi.org/10.3269/ebmj.2021.83
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