Original Articles
Vol. 16 (2021)

CONTRAST-ENHANCEMENT ULTRASOUND WITH MICROBUBBLES FOR SENTINEL NODE IDENTIFICATION: A CASE REPORT

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
107
Views
89
Downloads

Authors

Marco Materazzo
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy., Italy.
Marco Pellicciaro
marcopell62@gmail.com
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy, Italy.
Cataldo Caruso
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy, Italy.
Andrea Farinaccio
Department of Emergency and Admission, Critical Care Medicine, Pain Medicine and Anesthetic Science, Policlinico Tor Vergata University, Rome, Italy., Italy.
Mattia De Riso
Department of Clinical Sciences and Translational Medicine, University of Rome Tor Vergata, Rome, Italy, Italy.
Francesca Santori
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy, Italy.
Chiara Adriana Pistolese
Department of Biomedicine and Prevention, Policlinico Tor Vergata (PTV) University, Rome, Italy, Italy.
Tommaso Perretta
Department of Biomedicine and Prevention, Policlinico Tor Vergata (PTV) University, Rome, Italy, Italy.
Rosaria Meucci
Department of Biomedicine and Prevention, Policlinico Tor Vergata (PTV) University, Rome, Italy, Italy.
Agostoino Chiaravalloti
Department of Biomedicine and Prevention, Policlinico Tor Vergata (PTV) University, Rome, Italy; Nuclear Medicine Section, IRCCS Neuromed, Pozzilli, Italy., Italy.
Gianluca Vanni
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy., Italy.
Lymph node (LN) stage remains the primary prognostic discriminant in breast cancer. Lymphatic
mapping with sentinel LN (SLN) represents the gold standard for axillary staging in early breast
cancer (EBC), thus identification of a new contrast agent could provide clinicians with an
alternative to blue dye. AX-CES 1.2020, a prospective non-inferiority phase III trial designed to
evaluate the use of Sonovue (microbubbles with sulphur hexafluoride) under contrast enhanced
ultrasound (CEUS) as a SLN contrast agent. We herein present the first patient enrolled in the AX
CES 1.2020 trial. In the present clinical report, CEUS-SLN was a safe and feasible technique that
enhanced the same LN identified by m99Tc. Larger series are needed in order to investigate the role
of CEUS-SLN in EBC and further studies could evaluate the combination of the pathological and
ultrasonographic features of CEUS-SLN to predict axillary involvement.

Downloads

Download data is not yet available.

How to Cite



CONTRAST-ENHANCEMENT ULTRASOUND WITH MICROBUBBLES FOR SENTINEL NODE IDENTIFICATION: A CASE REPORT. (2025). EuroMediterranean Biomedical Journal, 16. https://www.embj.org/home/article/view/90
Copyright (c) 2025 The Author(s) Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.