Original Articles
Vol. 14 (2019)
https://doi.org/10.3269/1970-5492.2019.14.37
EFFICACY OF EARLY LOW-MOLECULAR-WEIGHT HEPARIN PROPHYLAXIS IN ELDERLY PATIENTS AFTER DEGENERATIVE SPINAL SURGERY: A BRIEF RETROSPECTIVE REVIEW
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: October 20 2025
Published: January 12 2026
Published: January 12 2026
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Many orthopaedic surgical procedures are potentially affected by deep vein thrombosis (DVT) and
Pulmonary Embolism (PE). DVT and PE are a clinical expression of the same pathological process called
venous thromboembolism (VTE). Low-molecular-weight heparin (LMWH) is approved/ recognized to be a
pharmacological solution to prevent VTE. The objective of the current study is twofold: (i) to assess the
effect of a therapeutic protocol with LWMH started 24 hours after surgery on systemic bleeding and ii) to
assess its effect on thrombosis and pulmonary embolism risk in patients undergoing early prophylaxis after
spine surgery. A consecutive cohort of 110 patients undergoing spinal surgery was tested. Fifty six cases
were spinal stenosis and 54 were degenerative thoracolumbar kypho-scoliosis. None of the patients withdrew
from the study. 2 patients manifested PE signs and a prophylactic protocol therapy with LMWH which was
started 24 hours after spine surgery resulted in a very low haemorrhage risk and low rate of PE and DVT
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How to Cite
EFFICACY OF EARLY LOW-MOLECULAR-WEIGHT HEPARIN PROPHYLAXIS IN ELDERLY PATIENTS AFTER DEGENERATIVE SPINAL SURGERY: A BRIEF RETROSPECTIVE REVIEW. (2026). EuroMediterranean Biomedical Journal, 14. https://doi.org/10.3269/1970-5492.2019.14.37
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