Original Articles
Vol. 3 (2008)
MR IMAGING IN ACUTE MARCHIAFAVA-BIGNAMI DISEASE: A CASE REPORT
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: April 13 2026
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Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism. MBD is characterized by primary demyelination of the corpus callosum. We report one case of MBD in which MR imaging showed high T2 FLAIR and diffusion-weighted signal intensity of the corpus callosum and in the deep and shallow white matter, in particular, of the temporo-occipital and fronto-parietal lobes. Here we describe the clinical case of a 57-year-old male patient, with a 30year history of alcohol (wine) brought to us in a state of mental confusion. He showed gait disturbance and lack of motor coordination.
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MR IMAGING IN ACUTE MARCHIAFAVA-BIGNAMI DISEASE: A CASE REPORT. (2026). EuroMediterranean Biomedical Journal, 3. https://doi.org/10.4081/embj.2008.559
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