Maggie Liberty, Eka Roina Megawati , Farhat, Evita Mayasari
High infectivity and death rates of COVID-19, as well as the restrictions imposed, inflicted significant psychological distress including COVID-19 anxiety syndrome. To overcome this situation, a vaccination program was implemented. However, many issues have emerged regarding the public acceptance of the vaccine. There are several factors that may affect vaccine acceptancy. This study aims to determine the relationship between COVID-19 anxiety syndrome and COVID-19 vaccine acceptancy. This research was developed using a cross-sectional research design. The samples included people in Medan, gathered based on the consecutive sampling method. All respondents received a questionnaire and the data collected was analyzed using Spearman Rho correlation analysis. This study showed that there was a significant relationship between COVID-19 anxiety syndrome and vaccine acceptancy (p<0,001), with moderate level of correlation (r=0,510). This study suggests that a higher level of COVID-19 anxiety syndrome leads to a higher acceptance of the vaccine.