MICROBIOLOGICAL ASPECTS OF CHLOROPHYLLIPT EXTRACT USED FOR PREVENTION OF CANDIDA POSTOPERATIVE COMPLICATIONS

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Maiia M Ananieva, Mariia O. Faustova, Galina A. Loban’, David S. Avetikov, Yaroslav O. Basarab, Volodymyr I. Ksonz

The purpose of this research paper was to investigate the chlorophyllipt extract fungicidal action against Candida spp. fungi. We studied the reference strain C. albicans, clinical strains of C. albicans and C. glabrata, isolated from patients of surgical units. The sensitivity assessment was performed on the derived strains for chlorophyllipt and ethanol using double serial dilutions according to the standard procedure. According to the results, the reference and clinical strains of Candida were sensitive to the action of the chlorophyllipt extract. The control strain of C. albicans was found to be the most sensitive at the time, as the antifungal effect of the extract studied against the clinical strains did not differ significantly from each other. In turn, it was found that ethanol had a weaker fungicidal action. The results of the study prove the antifungal effect of the chlorophyllipt extract against Candida spp. isolated from patients of surgical units.

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