Sebastiano Piana, Giuseppe Giordano, Diego Meo, Ilenia A.A. Vizzini, Viviana Lentini, Francesco Nicolosi, Gabriella Pellegriti, Vincenzo Magnano San Lio
Evaluate the effect of TAE in reducing intraoperative bleeding and algic symptoms in hypervascular bone metastases. Between January 2016 and May 2021, 101 embolizing procedures were performed in 83 patients with hypervascular bone metastases. The primary tumors were renal cell cancer, thyroid cancer and adrenal cancer. Indications were preintervention in 30 cases and palliative treatment in 53 cases; 18 patients treated with palliative TAE had a local recurrence of disease so we indicated a second palliative TAE. A grade 1 devascularization was obtained in 91 targeted lesions. In patients candidates for surgical exeresis, the intervention was performed within 48-72 hours after TAE and no cases of major intraoperative bleeding were reported. All patients who were not operated on, after TAE presented a significative pain relief. Between pain relief and devascularization grade we found a very strong correlation (r = 0.96). TAE reduces perioperative bleeding risk and improves algic symptoms as palliative treatment.